L-Zinex | Iberica Verheilen Pharmaceuticals

OUR PRODUCTS

ANTIBIOTICS

GASTRO-INTESTINAL PRODUCTS

ANTI-HISTAMINE

ANTI-HYPERTENSIVE

ANTI-EPILEPTIC/NEUROPATHIC PAIN

MULTIVITAMINS

FORMULATION

Each 5ml (1 teaspoonful) syrup contains Levocetirizine hydrochloride,2.5mg.

INDICATION

Allergic Rhinitis

For the relief of symptoms associated with seasonal allergic rhinitis in children ≥ 2 years and in adults.
For the relief of symptoms associated with perennial allergic rhinitis in children ≥ 6 months old in adults.

Chronic Idiopathic Urticaria

For treatment of uncomplicated skin manifestations of chronic idiopathic urticarial in children ≥ 6 months old and in adults.

DOSAGE AND ADMINISTRATION

This medicine should be taken orally, once a day at bedtime, with or without food. Children 6 months to 5 years old: 2.5 ml (1/2 teaspoonful)
Children 6 to 11 years old: 5 ml (1 teaspoonful)
Adults and Children≥ 12 years old: 10 ml(2 teaspoonfuls)

Renal impairment: Dosage adjustment should be done according to the degree of renal impairment as follows:

Dosage for Symptomatic Treatment of Allergic Rhinitis and Chronic Idiopathic Urticaria in Children ≥ 12 years old and Adults with Renal Impairment

Dosage of Renal Impairment	Creatinine Clearance(mL/min)	Oral Levocetirizine Dose
Mild	50 to 79	2.5(5mL)once a day
Moderate	30 to 49	2.5(5mL)once every 2 days
Severe	< 30	2.5(5mL)once every 3 days
End – stage renal disease Patients undergoing dialysis	< 10	CONTRAINDICATED

Hepatic Impairment: No dosage adjustment is necessary for hepatic impairment.

OVERDOSAGE

Drowsiness can be a symptom of overdosage occurring from administration of 50mg Cetirizine as a single dose. Overdosage in children may produce agitation. In case of massive overdosage, gastric lavage should be performed together with the usual supportive measures. To date, there is no specific antidote.

CONTRAINDICATION

Do not prescribe to patients with a history of hypersensitivity to any of the components of Cetirizine and lactating women since Cetirizine is excreted in breast milk.

PRECAUTIONS

Studies in health volunteer at 20 to 25mg/day have not revealed effects on alertness or reaction time.However, patients are advised not to exceed the recommended dose of driving or operating machinery.